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Your Gut on No Sulfur Wines

A new study gives credence to zero and low sulfur natural wine

Alice Feiring's avatar
Alice Feiring
Oct 10, 2025
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Do no-sulfur wines actually feel better in the gut? According to a new study, very possibly—giving more fuel to proof seekers in the debate: is natural wine healthier than the alternative.

Studies dealing with sulfites in wine are rare. The last one seems to have been out of Torino in 2019 and it gave credence to the notion that zero sulfur wine is metabolized in the blood quite differently than those with added sulfites. That was the first scientific weight giving a little more oomph to the natural wine no hangover debate, or at least one can drink more before the inevitable hangover blooms.

While not specifically about wine, another study published this summer caught my attention: Reduced Sulfur Diet Reshapes the Microbiome and Metabolome in Mild–Moderate Ulcerative Colitis. I started to wonder if colitis sufferers should be advised by their doctors to choose natural—if they choose to drink.

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